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Merck
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주요 문서

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SML0199

Sigma-Aldrich

Metaxalone

≥98% (HPLC)

동의어(들):

5-(3,5-Dimethylphenoxymethyl)-2-oxazolidinone, 5-[(3,5-Xylyloxy)methyl]-2-oxazolidinone, AHR 438, Metaxalon, Metazalone, Metazolone, NSC 170959

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C12H15NO3
CAS Number:
1665-48-1
Molecular Weight:
221.25
EC Number:
216-777-6
MDL number:
MFCD00867700
UNSPSC 코드:
12352200
PubChem Substance ID:
329825224
NACRES:
NA.77

Quality Level

100

분석

≥98% (HPLC)

양식

powder

색상

white to tan

solubility

DMSO: ≥2 mg/mL (warmed to 60 °C)

저장 온도

−20°C

SMILES string

Cc1cc(C)cc(OCC2CNC(=O)O2)c1

InChI

1S/C12H15NO3/c1-8-3-9(2)5-10(4-8)15-7-11-6-13-12(14)16-11/h3-5,11H,6-7H2,1-2H3,(H,13,14)

InChI key

IMWZZHHPURKASS-UHFFFAOYSA-N

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애플리케이션

Metaxalone may be used in cell signaling studies.

생화학적/생리학적 작용

Metaxalone is a muscle relaxant. The mechanism of action of metaxalone in humans is not fully understood. It was suggested that it acts through general central nervous system depression.
Metaxalone is effective to relieve pain due to acute skeletal muscle pain caused due to musculoskeletal conditions and sprains.

픽토그램

Exclamation mark
GHS07

신호어

Warning

유해 및 위험 성명서

H302

예방조치 성명서

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
101M4755V

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Justin L Poklis et al.
Journal of analytical toxicology, 28(6), 537-541 (2004-11-02)
The case history and toxicological findings of a fatal multi-drug overdose involving metaxalone (Skelaxin) are presented. Gas-liquid chromatography with flame-ionization detection and gas chromatography-mass spectrometry were used to determine the following drug concentrations (mg/L) in aortic blood: 19 mg/L metaxalone;
Rakshit Kanubhai Trivedi et al.
Scientia pharmaceutica, 80(2), 353-366 (2012-08-17)
A simple, sensitive and reproducible reversed phase ultra performance liquid chromatography (RP-UPLC) coupled with a photodiode array detector method was developed for the quantitative determination of metaxalone (META) in pharmaceutical dosage forms. The method is applicable to the quantification of
Peter P Toth et al.
Clinical therapeutics, 26(9), 1355-1367 (2004-11-09)
Low back pain is a leading reason for primary care visits. Many treatment options are available, but some lack scientific support. The aim of this review was to discuss the etiology of low back pain and the relative risks and

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