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Merck
모든 사진(1)

주요 문서

SML0189

Sigma-Aldrich

Indinavir sulfate salt hydrate

≥98% (HPLC), powder, antiretroviral agent

동의어(들):

2,3,5-Trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate hydrate, Crixivan hydrate, L-735,524 hydrate, MK-639 hydrate

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About This Item

실험식(Hill 표기법):
C36H47N5O4·H2SO4 · xH2O
Molecular Weight:
711.87 (anhydrous basis)
UNSPSC 코드:
51111800
NACRES:
NA.77

제품명

Indinavir sulfate salt hydrate, ≥98% (HPLC)

Quality Level

분석

≥98% (HPLC)

양식

powder

저장 조건

desiccated

색상

white to tan

solubility

H2O: ≥15 mg/mL

주관자

Merck & Co., Inc., Kenilworth, NJ, U.S.

저장 온도

2-8°C

애플리케이션

Indinavir sulfate salt hydrate may be used in HIV-related cell signaling studies.

생화학적/생리학적 작용

Indinavir sulfate is an antiretroviral; HIV Protease Inhibitor
Indinavir sulfate is an antiviral HIV protease inhibitor.
Indinavir sulfate suppresses the replication of HIV and is an important component of antiretroviral therapy for initial treatment of HIV infection. It is known to cause renal and urologic toxicity.

특징 및 장점

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Ryan D Cooper et al.
Nephron. Clinical practice, 118(3), c262-c268 (2011-01-08)
The introduction of potent combination antiretroviral therapy (ART) in the treatment of HIV infection has permitted reliable control of disease progression and has markedly improved survival among people with HIV. As a result, health care providers and patients have shifted
Benjamin Seyer et al.
Journal of neurochemistry, 153(4), 485-494 (2019-09-27)
Ethyl2-acetylamino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylate (HFI-419), the benzopyran-based inhibitor of insulin-regulated aminopeptidase (IRAP), has previously been shown to improve spatial working and recognition memory in rodents. However, the mechanism of its cognitive-enhancing effect remains unknown. There is a close correlation between dendritic spine density

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We offer agonists, antagonists, modulators and other bioactive small molecules for immune system signaling target identification and validation, as well as a variety of antibiotics, antivirals, and antifungals.

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