SML0174

GPR35 Agonist, Compound 10

≥98% (HPLC)

• 동의어(들): 2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
• 실험식(Hill 표기법): C₁₂H₉NO₅S
• CAS Number: 123021-85-2
• Molecular Weight: 279.27
• MDL number: MFCD01835940
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825204
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to tan
• solubility: DMSO: ≥5 mg/mL at ~60 °C
• 저장 온도: 2-8°C
• SMILES string: OC(=O)COc1ccc(cc1)\C=C2/SC(=O)NC2=O
• InChI: 1S/C12H9NO5S/c14-10(15)6-18-8-3-1-7(2-4-8)5-9-11(16)13-12(17)19-9/h1-5H,6H2,(H,14,15)(H,13,16,17)/b9-5-
• InChI key: WXMCOLGPDOYHNK-UITAMQMPSA-N

설명

애플리케이션

GPR35 Agonist, Compound 10, may be used in GPR35-mediated cell signaling studies.

생화학적/생리학적 작용

GPR35 Agonist

GPR35 agonist Compound 10 is a GPR35 agonist the binds with higher affinity than other known agonists, such as kynurenic acid and zaprinast. Compound 10 was more potent than zaniprast (pEC50 = 5.3 vs 4.18) for recombinantly expressed human GPR35, and unlike zaprinast, is equipotent for human and rat GPR35

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable