추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
광학 활성
[α]/D +54 to +70°, c = 0.5 in methanol
색상
white to tan
solubility
DMSO: ≥20 mg/mL (warmed)
주관자
Bristol-Myers Squibb
Sanofi Aventis
저장 온도
2-8°C
SMILES string
OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl
InChI
1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1
InChI key
FDEODCTUSIWGLK-RSAXXLAASA-N
유전자 정보
human ... P2RY12(64805)
애플리케이션
(S)-(+)-Clopidogrel hydrogensulfate was used as standard in HPLC-MS/MS to detect clopidogrel and its thiol derivative in human plasma.
생화학적/생리학적 작용
(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent. It specifically and irreversibly inhibits the Purinoceptor P2Y12 subtype which inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer.
특징 및 장점
This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Bristol-Myers Squibb and Sanofi Aventis. To browse the list of other pharma-developed compounds, Approved Drugs, and Drug Candidates, click here.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 880(1), 132-139 (2011-12-16)
A sensitive, selective, and rapid ultra-high performance liquid chromatography-tandem mass spectrometry (uHPLC-MS/MS) was developed for the simultaneous quantification of clopidogrel (Plavix(®)) and its derivatized active metabolite (CAMD) in human plasma. Derivatization of the active metabolite in blood with 2-bromo-3'-methoxy acetophenone
Echocardiography (Mount Kisco, N.Y.), 32(6), 1003-1008 (2014-10-08)
This study aimed to examine the application of intravascular ultrasound (IVUS) in ST-segment elevation myocardial infarction (STEMI) patients with high thrombus burden (thrombus grade ≥3) undergoing emergency diagnosis and primary percutaneous coronary intervention. Eighty STEMI patients were enrolled and randomly
Phytotherapy research : PTR, 30(11), 1886-1892 (2016-11-05)
Ginkgo biloba extract (GBE), a traditional herbal product used worldwide as both medicine and supplement, is often supplied with clopidogrel for the treatment of cerebrovascular diseases. The aim of the current study was to explore the effect of GBE on
PLoS pathogens, 15(4), e1007625-e1007625 (2019-04-23)
Dengue virus (DENV) infection, the most common mosquito-transmitted viral infection, can cause a range of diseases from self-limiting dengue fever to life-threatening dengue hemorrhagic fever and shock syndrome. Thrombocytopenia is a major characteristic observed in both mild and severe dengue
Cancer cell, 40(10), 1111-1127 (2022-09-17)
Glioblastoma (GBM) is poorly responsive to therapy and invariably lethal. One conceivable strategy to circumvent this intractability is to co-target distinctive mechanistic components of the disease, aiming to concomitantly disrupt multiple capabilities required for tumor progression and therapeutic resistance. We
문서
P2 Receptors: P2Y G-Protein Family
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