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Merck
모든 사진(1)

주요 문서

SMB01042

Sigma-Aldrich

Allocryptopin

≥90% (LC/MS-ELSD)

동의어(들):

β-Allocryptopine, γ-Homochelidonine, Fagarine I

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About This Item

실험식(Hill 표기법):
C21H23NO5
CAS Number:
Molecular Weight:
369.41
MDL number:
UNSPSC 코드:
12352205
NACRES:
NA.25

생물학적 소스

plant

분석

≥90% (LC/MS-ELSD)

양식

solid

분자량

369.41

solubility

water: slightly soluble

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

−20°C

SMILES string

N1(CCc2c(cc4c(c2)OCO4)C(=O)Cc3c(c(c(cc3)OC)OC)C1)C

InChI

1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3

InChI key

HYBRYAPKQCZIAE-UHFFFAOYSA-N

일반 설명

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

애플리케이션

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

생화학적/생리학적 작용

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

특징 및 장점

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

기타 정보

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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