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Merck
모든 사진(1)

주요 문서

SML1853

Sigma-Aldrich

Kaempferitrin

≥97% (NMR)

동의어(들):

3,7-Bis((6-deoxy-α-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kaempferol 3,7-dirhamnoside, Lespedin, Lespenefril, Lespenephryl

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About This Item

실험식(Hill 표기법):
C27H30O14
CAS Number:
Molecular Weight:
578.52
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

생물학적 소스

(Cinnamomum sp.)

Quality Level

분석

≥97% (NMR)

양식

powder

저장 조건

desiccated
protect from light

색상

white to beige

저장 온도

−20°C

SMILES string

OC(C=C1)=CC=C1C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(C4=C(O)C=C(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4O2)=O

InChI

1S/C27H30O14/c1-9-17(30)20(33)22(35)26(37-9)39-13-7-14(29)16-15(8-13)40-24(11-3-5-12(28)6-4-11)25(19(16)32)41-27-23(36)21(34)18(31)10(2)38-27/h3-10,17-18,20-23,26-31,33-36H,1-2H3/t9-,10-,17-,18-,20+,21+,22+,23+,26-,27-/m0/s1

InChI key

PUPKKEQDLNREIM-QNSQPKOQSA-N

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생화학적/생리학적 작용

Kaempferitrin (Lespenefril) is a naturally-occurring kaempferol glycoside with antimicrobial, antioxidant, and anti-inflammatory activities.
Kaempferitrin is a flavonol glycoside, present in several plants, predominant in Bauhinia. It is known to stimulate insulin signaling pathway and induces glucose uptake, by mediating GLUT4 (glucose transporter 4) translocation to adipocyte membrane.. Kaempferitrin aids in lowering blood glucose level and therefore helps to improve the glycemic condition in diabetic animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Julia Cassani et al.
Molecules (Basel, Switzerland), 19(12), 21442-21461 (2014-12-24)
We evaluated the antidepressant-like effect of kaempferitrin (Km) isolated from the plant Justicia spicigera (Asteraceae), which is used in traditional medicine for relieving emotional disorders, such as "la tristeza" (sadness or dysthymia) and "el humor" (mood changes). The actions of
Discovery and Development of Antidiabetic Agents from Natural Products, 118-118 (2016)
Plants with Anti-Diabetes Mellitus Properties, 88-88 (2016)
Xue-Qin Ma et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 22(13), 1159-1162 (2015-11-26)
Podocarpium podocarpum (DC.), an edible and medicinal plant popularly used for the treatment of bruises and fracture in Chinese folk medicine, has been proved to possess significant antiosteoporotic effect in our latest research. Our study aimed to investigate the in
Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes
Tzeng YM, et al.
European Journal of Pharmacology, 607(1-3), 27-34 (2009)

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