SMB01024

Diuvaretin

≥90% (LC/MS-ELSD)

• 동의어(들): 1-[2,4-dihydroxy-3,5-bis[(2-hydroxyphenyl)methyl]-6-methoxyphenyl]-3-phenylpropan-1-one
• 실험식(Hill 표기법): C₃₀H₂₈O₆
• CAS Number: 61463-04-5
• Molecular Weight: 484.54
• MDL number: MFCD18975655
• UNSPSC 코드: 12352205
• NACRES: NA.25

속성

• 생물학적 소스: plant
• 분석: ≥90% (LC/MS-ELSD)
• 양식: solid
• 분자량: 484.54
• solubility: water: slightly soluble
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: −20°C
• SMILES string: O(C)c1c(c(c(c(c1C(=O)CCc4ccccc4)O)Cc3c(cccc3)O)O)Cc2c(cccc2)O
• InChI: 1S/C30H28O6/c1-36-30-23(18-21-12-6-8-14-25(21)32)28(34)22(17-20-11-5-7-13-24(20)31)29(35)27(30)26(33)16-15-19-9-3-2-4-10-19/h2-14,31-32,34-35H,15-18H2,1H3
• InChI key: KDEMELRYKGOXDL-UHFFFAOYSA-N

설명

일반 설명

Diuvaretin, a dihydrochalcone, is a natural product commonly available from Dipteryx odorata, Uvaria acuminata and Uvaria chamae plants. This plant metabolite exhibits various biological activities such as anti-inflammatory, antioxidant, antineoplastic, anti-angiogenic, and antimalarial properties.

애플리케이션

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

생화학적/생리학적 작용

Diuvaretin exhibits cytotoxicity towards human promyelocytic leukemia HL-60 cells. It has a role as a metabolite, an antineoplastic agent and an antimalarial.

Diuvaretin inhibits NF-kB activation, hindering inflammation and cancer. It also suppresses tumor cell proliferation, induces apoptosis, and diminishes tumor growth and angiogenesis in mouse cancer models.

특징 및 장점

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

기타 정보

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable