SMB00377

Magnoflorine

≥98% (HPLC)

• 동의어(들): (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol
• 실험식(Hill 표기법): C₂₀H₂₄NO₄
• CAS Number: 2141-09-5
• Molecular Weight: 342.41
• MDL number: MFCD09031380
• UNSPSC 코드: 12352205
• PubChem Substance ID: 329824978
• NACRES: NA.25

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 형태: powder
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: 2-8°C
• SMILES string: OC1=C(OC)C=C2CC[N+](C)(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C4C1=C32
• InChI: 1S/C20H23NO4/c1-21(2)8-7-12-10-15(25-4)20(23)18-16(12)13(21)9-11-5-6-14(24-3)19(22)17(11)18/h5-6,10,13H,7-9H2,1-4H3,(H-,22,23)/p+1/t13-/m0/s1
• InChI key: YLRXAIKMLINXQY-ZDUSSCGKSA-O

설명

일반 설명

Magnoflorine is a secondary metabolite and an alkaloid with a quaternary aporphine configuration. It can be found in roots, rhizomes, stems, barks, or seeds of many herbal plants such as Caulophyllum thalictroides (blue cohosh), Arisolochai bracteate, P. amurense, S. acutum, Tinospora crispa, Coptidis rhizome, etc. Magnoflorine constitutes approximately 65 % of the total alkaloids in roots and rhizomes of blue cohosh. It is also known as thalictrine and escholine.

애플리케이션

Magnoflorin has been used to test its contractile effects on isolated mouse uterine smooth muscle tissues and on isolated strips of Mus musculus distal colon smooth muscle tissues.

생화학적/생리학적 작용

Magnoflorine possesses several biochemical and pharmacological properties such as antioxidant, anti-inflammatory, immunomodulatory, anti-diabetic, anti-fungal, cardiovascular protective, and neuropsychological. It also acts as an α-tyrosinase inhibitor. It helps to increase pro-inflammatory responses induced by lipopolysaccharide (LPS). It exerts antitumor, anti-cancer activities by inhibiting gastric cancer progression gastric cancer cell xenograft mouse model.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302 + H312 + H332
• 예방조치 성명서: P261 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable