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Merck
모든 사진(1)

문서

SMB00177

Sigma-Aldrich

Kaurenoic acid

≥95% (LC/MS-ELSD)

동의어(들):

Ent-kaurenoic acid, Kaur-16-en-18-oic acid, Kauren-19-oic acid, Kaurenic acid, Cunabic acid

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About This Item

실험식(Hill 표기법):
C20H30O2
CAS Number:
Molecular Weight:
302.45
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.25

분석

≥95% (LC/MS-ELSD)

형태

solid

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

−20°C

SMILES string

C=C1C[C@@]23CC[C@]4([H])[C@@](C(O)=O)(C)CCC[C@@]4(C)[C@]2([H])CC[C@@H]1C3

InChI

1S/C20H30O2/c1-13-11-20-10-7-15-18(2,16(20)6-5-14(13)12-20)8-4-9-19(15,3)17(21)22/h14-16H,1,4-12H2,2-3H3,(H,21,22)/t14-,15+,16+,18-,19-,20-/m1/s1

InChI key

NIKHGUQULKYIGE-OTCXFQBHSA-N

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일반 설명

Natural product derived from plant source.

생화학적/생리학적 작용

Kaurenoic acid (KA) is a diterpene which displays selective antibacterial activity against Gram-positive bacteria. Kaurenoic acid exhibits uterine relaxant activity via calcium blockade and opening ATP-sensitive potassium channels.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Effect of the kaurenoic acid on genotoxicity and cell cycle progression in cervical cancer cells lines.
Silvia Maria Machado da Rocha et al.
Toxicology in vitro : an international journal published in association with BIBRA, 57, 126-131 (2019-03-02)
Simone Ribeiro Lucho et al.
Physiology and molecular biology of plants : an international journal of functional plant biology, 24(5), 767-779 (2018-08-29)
Stevia rebaudiana is an important source of natural steviol glycosides and is of increasing interest in various fields of study. Therefore, understanding the molecular processes regulating its metabolism is of great importance. In this study, the stability of seven reference
Ran Joo Choi et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(8-9), 677-682 (2011-01-08)
This study investigates the anti-inflammatory effects of a diterpenoid, kaurenoic acid, isolated from the root of Aralia continentalis (Araliaceae). To determine its anti-inflammatory effects, LPS-induced RAW264.7 macrophages were treated with different concentrations of kaurenoic acid and carrageenan-induced paw edema mice
J P Mestres et al.
Fitoterapia, 82(4), 585-590 (2011-01-26)
Espeletiinae are plants which grow above 3000 m of altitude in the Northern Andes and kaurenic acid was extracted from the leaves of Coespeletia moritziana. This compound has shown a wide range of biological activities, including cytotoxicity which is efficient
B C Cavalcanti et al.
Mutation research, 701(2), 153-163 (2010-07-06)
Kaurane diterpenes are considered important compounds in the development of new highly effective anticancer chemotherapeutic agents. Genotoxic effects of anticancer drugs in non-tumour cells are of special significance due to the possibility that they induce secondary tumours in cancer patients.

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