추천 제품
분석
≥95% (HPLC)
양식
lyophilized
구성
Peptide Content, ≥80%
저장 조건
protect from light
저장 온도
−20°C
유전자 정보
human ... CASP9(842)
Amino Acid Sequence
Ac-Leu-Glu-His-Asp-al
생화학적/생리학적 작용
Ac-Leu-Glu-His-Asp-al, or Ac-LEHD-CHO, is a cell-permeable tetrapeptide aldehyde. It is an inhibitor of caspase-9. Its target of action has been proposed to be the mitochondrial pathway of apoptosis. Ac-LEHD-CHO has also been postulated to prevent cleavage of caspase-8, and partly to prevent cleavage of caspase-3.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Daniel Purich
The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads (2017)
PP2A mediates apoptosis or autophagic cell death in multiple
myeloma cell lines
myeloma cell lines
Hang Zhou
Oncotarget (2017)
Hang Zhou et al.
Oncotarget, 8(46), 80770-80789 (2017-11-09)
The crosstalk between apoptosis and autophagy contributes to tumorigenesis and cancer therapy. The process by which BetA (betulinic acid), a naturally occurring triterpenoid, regulates apoptosis and autophagy as a cancer therapy is unclear. In this study, we show for the
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