콘텐츠로 건너뛰기
Merck
모든 사진(2)

Key Documents

SAB5801054

Sigma-Aldrich

Goat Anti-Chicken IgY HRP Alpaca Heavy chain only Antibody

recombinant Alpaca(VHH) Nano antibody

동의어(들):

Recombinant Alpaca single variable domain secondary Nanobody

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

alpaca

재조합

expressed in HEK 293 cells (Human cell line)

결합

horse radish peroxidase (HRP)

항체 형태

affinity purified immunoglobulin

항체 생산 유형

secondary antibodies

클론

recombinant monoclonal

형태

lyophilized solid

분자량

100 kDa

종 반응성

chicken, Alpaca

기술

ELISA: 1:10000-1:50000
western blot: 1:10000-1:50000

크기

0.1 mL

색상

colorless

동형

VHH

배송 상태

wet ice

저장 온도

2-8°C

일반 설명

Goat Anti-Chicken IgY HRP Alpaca Heavy chain only Antibody is designed to specifically detect chicken IgY. It is a monoclonal, recombinant, goat IgG Fc fused single domain antibody to chicken IgY coupled to HRP. Based on immunoelectrophoresis and/or ELISA, Goat Anti-Chicken IgY HRP Alpaca Heavy chain only Antibody reacts with the chicken IgY selectively but not with mouse, rabbit, human, cynomolgus, rat, goat IgG.

Hens egg yolk immunoglobulins IgY can be transferred from the serum of mother hen to the offspring egg yolk to acquire immunity. In the immunodiagnostic technologies, IgY is an excellent antibody for using in immunological assays involving mammalian sera, due to discriminative properties of IgY compared to mammalian IgG, as IgY does not react with the rheumatoid factor and human anti-mouse IgG antibodies do not activate the complement system and do not bind to Fc receptor. Also, they have poor cross reactivity to mammalian IgG due to immunological differences. IgY does not contain a hinge region but does contain an additional constant domain. The whole IgY molecule possesses both the Fc region and the Fab region, which possessing the epitope-recognition site. The IgYcontains two heavy and light chains. The common IgY is monomeric with a molecular weight of approximately 170 kDa.

VHH are single-domain antibodies derived from the variable regions of heavy chain of Camelidae immunoglobulin. The size of VHH is extremely small(less than15KDa) compared to other forms of antibody fragment, which significantly increase the permeability of VHH. Thus VHH is considered of great value for research, diagnostics and therapeutics.

특이성

Fc region of chicken IgY
Isotype: VHH domain of alpaca IgG2b/2c fused to goat IgG Fc

면역원

Recombinant Alpaca single variable domain secondary nano antibody

포장

100 μg in Glass bottle

물리적 형태

Lyophilized from 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose

재구성

Add 100uL dH2O or 100uL dH2O with 50% Glycerol to a final concentration of 1mg/mL

저장 및 안정성

After reconstitution, store at –20 °C(Avoid freeze / thaw cycles). Protect from light. Stable for 12 months at -20°C

기타 정보

No cross-reactivity with mouse, rabbit, human, cynomolgus, rat, goat IgG

적합한 제품을 찾을 수 없으신가요?  

당사의 제품 선택기 도구.을(를) 시도해 보세요.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Aquatic Chronic 3 - Skin Sens. 1

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.