SAB5702859

Anti-KRAS+HRAS+NRAS Antibody

rabbit monoclonal, 6S6F3

• 동의어(들): ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 제품명: Anti-KRAS+HRAS+NRAS Antibody, clone 6S6F3, Rabbit Monoclonal,
• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 6S6F3, monoclonal
• 양식: liquid
• 분자량: 20 kDa
• 종 반응성: rat, human, rat
• 농도: 0.30 mg/mL
• 기술: immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 색상: colorless
• 동형: IgG
• 면역원 서열: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQI
• UniProt 수납 번호: P01111; P01112; P01116_
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... NRAS(4893)

설명

일반 설명

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

면역원

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NRAS (P01111).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

애플리케이션

WB, IF/ICC

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1