생물학적 소스
rabbit
Quality Level
material
colorless
클론
4X6E1, monoclonal
양식
liquid
분자량
28 kDa
종 반응성
human, rat, rat
농도
0.2 mg/mL
기술
western blot: 1:500 - 1:2000
색상
colorless
동형
IgG
면역원 서열
MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDI
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... YWHAE(7531)
일반 설명
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
면역원
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 epsilon (P62258).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
애플리케이션
WB
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
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