SAB5702261

Anti-MCM2 Antibody, clone 0Q10S9, Rabbit Monoclonal

• 동의어(들): MCM2,BM28,CCNL1,CDCL1,D3S3194,DFNA70,MITOTIN,cdc19
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 0Q10S9, monoclonal
• 형태: liquid
• 분자량: 125 kDa
• 종 반응성: human, rat, rat
• 농도: 0.38 mg/mL
• 기술: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:100 - 1:200; western blot: 1:500 - 1:2000
• 색상: colorless
• 동형: IgG
• 면역원 서열: MAESSESFTMASSPAQRRRGNDPLTSSPGRSSRRTDALTSSPGRDLPPFEDESEGLLGTEGPLEEEEDGEELIGDGMERDYRAIPELDAYEAEGLALDDE
• UniProt 수납 번호: P49736
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MCM2(4171)

설명

일반 설명

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

면역원

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MCM2 (P49736).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

애플리케이션

WB, IHC, IF/ICC

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1