SAB5702066

Anti-Acetyl-p53-K382 Antibody, clone 0, Rabbit Monoclonal

• 동의어(들): BCC7,LFS1,P53,TRP53,p53,TP53,BMFS5
• UNSPSC 코드: 12352203
• NACRES: NA.46

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• material: colorless
• 클론: 7Z8X9, monoclonal
• 형태: liquid
• 분자량: 53 kDa
• 종 반응성: mouse, mouse
• 농도: 0.90 mg/mL
• 색상: colorless
• 동형: IgG
• 면역원 서열: HKKLM
• UniProt 수납 번호: P04637
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TP53(7157)

설명

일반 설명

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

면역원

A synthetic acetylated peptide around K382 of human p53 (NP_000537.3).

PBS with 0.05% proclin300,50% glycerol,pH7.3.

애플리케이션

DB, WB

안전성 정보

• 픽토그램: GHS07,GHS09
• 신호어: Warning
• 유해 및 위험 성명서: H317,H411
• 예방조치 성명서: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 2 - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3