SAB5701332

Anti- DNMT1 antibody produced in rabbit

• UNSPSC 코드: 12352203
• NACRES: NA.43
• 클론: monoclonal
• application: IHC; WB
• 종 반응성: rat, human, mouse
• 기술: immunohistochemistry: 1:50-1:200; western blot: 1:5000-1:8000

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: monoclonal
• 양식: liquid
• 종 반응성: rat, human, mouse
• 농도: 2.05 mg/mL
• 기술: immunohistochemistry: 1:50-1:200; western blot: 1:5000-1:8000
• UniProt 수납 번호: P26358
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... DNMT1(1786)

설명

일반 설명

This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

면역원

A synthesized peptide derived from human DNMT1.

물리적 형태

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable