SAB5700294

Anti-Phospho-EIF4EBP1-T37/46 antibody produced in rabbit

• 동의어(들): 4E-BP1, 4EBP1, BP-1, EIF4EBP1, PHAS-I
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 12
• 종 반응성: human, mouse
• 농도: 1.23 mg/ml
• 기술: western blot: 1:500-1:2000
• UniProt 수납 번호: Q13541
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pThr37/pThr46)
• 유전자 정보: human ... EIF4EBP1(1978)

설명

일반 설명

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

면역원

A phospho specific peptide corresponding to residues surrounding T37/46 of human EIF4EBP1

물리적 형태

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

저장 및 안정성

Store at -20℃. Avoid freeze / thaw cycles.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable