SAB5300177

Monoclonal Anti-SOX2 antibody produced in mouse

clone 10F10, ascites fluid

• 동의어(들): Sox-2, Sox2, lcc, ysb
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: 10F10, monoclonal
• 분자량: 34 kDa
• 종 반응성: human
• 기술: direct ELISA: 1:10,000; immunohistochemistry: 1:200-1:1,000; indirect immunofluorescence: 1:200-1:1,000; western blot: 1:500-1:2,000
• 동형: IgG1
• UniProt 수납 번호: P48431
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SOX2(20674)

설명

일반 설명

SOX2 (sex-determining region Y-box 2) is a transcription factor consisting of 317 amino acids. It has an HMG (high mobility group box) domain and is a critical transcription regulator of normal stem cell. It is located on human chromosome 3q26.3.

면역원

Purified recombinant fragment of human SOX2 expressed in E.coli.
Mouse monoclonal antibody raised against SOX2

애플리케이션

Monoclonal Anti-SOX2 antibody has been used as a core pluripotency factor to regulate stem cell pluripotency.

생화학적/생리학적 작용

SOX2 (sex-determining region Y-box 2) down-regulation reduces the stem cell count, that affects breast cancer cells in initiating tumor progression. It participates in chemoresistance and regular lung cancer therapies. In mouse, SOX2 plays an important role in branching morphogenesis and regulating lung epithelial cell differentiation.

물리적 형태

Ascitic fluid containing 0.03% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable