SAB5200921

Monoclonal Anti-Notch1 - Percp antibody produced in mouse

clone S253-32, purified immunoglobulin

• 동의어(들): Anti-Motch, Anti-Neurogenic locus notch homolog protein 1, Anti-Neurogenic locus notch protein homolog, Anti-TAN1
• UNSPSC 코드: 12352203
• NACRES: NA.41
• 결합: Peridinin-Chlorophyll-Protein Complex
• application: ICC; WB
• 클론: S253-32, monoclonal
• 종 반응성: mouse, rat, human
• citations: 5
• 기술: immunocytochemistry: suitable; western blot: suitable

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: Peridinin-Chlorophyll-Protein Complex
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: S253-32, monoclonal
• 양식: buffered aqueous solution
• 분자량: antigen predicted mol wt >270, ~120 kDa
• 종 반응성: mouse, rat, human
• 농도: 1 mg/mL
• 기술: immunocytochemistry: suitable; western blot: suitable
• 동형: IgG1
• NCBI 수납 번호: NP_032740.3
• UniProt 수납 번호: Q07008
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Notch1(18128)

설명

일반 설명

The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros.

면역원

Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1

생화학적/생리학적 작용

The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

PBS pH7.4, 50% glycerol, 0.09% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable