SAB4702061

Monoclonal Anti-CD10 APC-Cyanine7 produced in mouse

• 동의어(들): Atriopeptidase, CALLA, Enkephalinase, MME, Neprilysin, Neutral endopeptidase
• UNSPSC 코드: 12352203

속성

• 결합: APC-Cy7 conjugate
• Quality Level: 100
• 항체 생산 유형: primary antibodies
• 클론: MEM-78, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human
• 기술: flow cytometry: suitable
• 동형: IgG1
• UniProt 수납 번호: P08473
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MME(4311)

설명

일반 설명

CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.

특이성

The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

면역원

NALM-6 human pre-B cell line

물리적 형태

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

제조 메모

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

저장 및 안정성

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

기타 정보

The antibody solution should be gently mixed before use.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable