SAB4700391

Monoclonal Anti-CD11c-APC antibody produced in mouse

clone BU15, purified immunoglobulin, buffered aqueous solution

• 동의어(들): Anti-ITGAX
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: Allophycocyanin conjugate
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: BU15, monoclonal
• 양식: buffered aqueous solution
• 종 반응성: human, monkey, canine
• 기술: flow cytometry: suitable
• 동형: IgG1
• NCBI 수납 번호: NM_000887.3
• UniProt 수납 번호: P20702
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ITGAX(3687)

설명

일반 설명

Cluster of differentiation 11c (CD11c), also known as integrin subunit α X (ITGAX), is an antigen receptor, encoded by the gene mapped to human chromosome 16p11.2. The encode protein belongs to the adhesion molecule integrin family and is mainly expressed in natural killer cells, macrophages and even some activated B and T cells.

The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.

면역원

Dendritic cells of synovial fluid

애플리케이션

The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests.

생화학적/생리학적 작용

Cluster of differentiation 11c (CD11c) delivers co-stimulatory signals to activated lymphocytes. Elevated expression of the gene decreased the risk of death and relapse in gastric cancer (GC) patients. The protein can be considered as an alternative prognosis marker for GC. Overexpression of CD11c in CD8⁺ cells might lead to the development of Behcet′s disease (BD).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable