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Merck
모든 사진(13)

주요 문서

SAB4504393

Sigma-Aldrich

Anti-phospho-eNOS (pSer1176) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-ECNOS, Anti-eNOS

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 133 kDa

종 반응성

rat, human, mouse

농도

~1 mg/mL

기술

ELISA: 1:20000
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

phosphorylation (pSer1176)

유전자 정보

human ... NOS3(4846)

일반 설명

Nitric oxide synthase 3 (NOS3), also known as endothelial nitric oxide synthase (eNOS), is encoded by the gene mapped to human chromosome 7q35-36. The gene consists of 26 exons.

면역원

The antiserum was produced against synthesized peptide derived from human eNOS around the phosphorylation site of Ser1176.

Immunogen Range: 1144-1193

생화학적/생리학적 작용

Nitric oxide synthase 3 (NOS3) has been studied as a modulator of vascular function and is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated with coronary artery disease.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Association between three eNOS polymorphisms and intracranial aneurysms risk: a meta-analysis.
Yang C, et al.
Medicine, 94(4) (2015)
Association between three eNOS polymorphisms and intracranial aneurysms risk: a meta-analysis.
Yang C, et al.
Medicine, 94(4) (2015)
Marwa Ben Ali et al.
Genetic testing and molecular biomarkers, 19(4), 203-208 (2015-03-10)
Nitric oxide (NO), produced by the enzyme endothelial nitric oxide synthase (eNOS), has critical roles in the regulation of vascular homeostasis and prevention of atherogenesis by inhibiting leukocytes, platelet activation, and smooth muscle cell proliferation. There is strong experimental and
Sherif Hafez et al.
Translational stroke research, 11(4), 851-860 (2019-12-21)
Physical exercise is known to reduce cardiovascular risk but its role in ischemic stroke is not clear. It was previously shown that an acute single bout of exercise reduced increased eNOS activation in the heart and reduced myocardial infarction. However
Bing Yi et al.
Arteriosclerosis, thrombosis, and vascular biology, 35(10), 2153-2160 (2015-08-22)
Endothelial nitric oxide synthase (eNOS) is an important regulator of vascular function and its expression is regulated at post-transcriptional levels through a yet unknown mechanism. The purpose of this study is to elucidate the post-transcriptional factors regulating eNOS expression and

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