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Merck
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Key Documents

SAB4502013

Sigma-Aldrich

Anti-ENOS antibody produced in rabbit

affinity isolated antibody

동의어(들):

Constitutive NOS, EC-NOS, ECNOS, Endothelial NOS, cNOS

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen 133 kDa

종 반응성

human, rat, mouse

농도

~1 mg/mL

기술

ELISA: 1:40000
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... NOS3(4846)

일반 설명

Anti-ENOS Antibody detects endogenous levels of total ENOS protein.
The ENOS (endothelial nitric oxide synthase) gene is mapped to human chromosome 7q36.1. ENOS is expressed predominantly in the endothelial cells.

면역원

The antiserum was produced against synthesized peptide derived from human eNOS.

Immunogen Range: 581-630

애플리케이션

Anti-ENOS antibody produced in rabbit has been used in SDS-PAGE and western blotting.

생화학적/생리학적 작용

ENOS (endothelial nitric oxide synthase) is responsible for the production of nitric oxide. eNOS is known to stimulate vasodilation and regulate inflammation and myocyte function. Impairment of endothelium-dependent vasodilatation that is observed in acute hyperglycaemia condition is due to suppression of ENOS. The gene might be involved in lipolysis. Variation in ENOS might lead to Henoch-Schönlein purpura. ENOS polymorphism affects the NO concentration in plasma.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

The role of the eNOS G894T and T-786C gene polymorphism in the development of ascites in cirrhosis.
Yildirim O
European Review for Medical and Pharmacological Sciences, 20(22), 4725-4730 (2016)
(-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: Potential role of endothelial nitric oxide synthase.
Ramirez-Sanchez I
Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease, 13(3), 201-210 (2016)
Mechanisms underlying the hypotensive and vasodilator effects of Ru(terpy)(bdq)NO](3+), a nitric oxide donor, differ between normotensive and spontaneously hypertensive rats.
Potje SR
European Journal of Pharmacology, 741, 222-229 (2014)
Association of Endothelial Nitric Oxide Synthase Gene Polymorphism with Susceptibility and Nephritis Development of Henoch-Schonlein Purpura in Chinese Han Children.
Wang A
Genetic Testing and Molecular Biomarkers, 21(6), 373-381 (2017)
Heat-shock protein 60 of Porphyromonas gingivalis may induce dysfunction of human umbilical endothelial cells via regulation of endothelial-nitric oxide synthase and vascular endothelial-cadherin.
Wu C
Biomedical Reports, 5(2), 243-247 (2016)

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