SAB4502446

Anti-CXCR7 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): CXCR-7, CXCR7, G-protein coupled receptor 159, G-protein coupled receptor RDC1, chemokine orphan receptor 1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 41 kDa
• 종 반응성: rat, mouse, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI 수납 번호: P25106
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CXCR7(57007)

설명

일반 설명

Anti-CXCR7 Antibody detects endogenous levels of total CXCR7 protein.

CXC- Chemokine receptor 7 (CXCR7) protein is a seven-transmembrane G-protein coupled receptor (GPCR). It is expressed in the heart tissues, fetal hematopoietic cells, embryonic neuronal, and activated endothelium. CXCR7 gene is mapped on the human chromosome at 2q37.3.

면역원

The antiserum was produced against synthesized peptide derived from human CXCR7.

Immunogen Range: 311-360

생화학적/생리학적 작용

CXC- Chemokine receptor 7 (CXCR7) protein interacts with chemokine ligands CXCL11 and CXCL12. This protein shuffles between the plasma membrane and endosomal compartments irrespective of the presence of a ligand such as CXCL11 and 12. CXCR7 protein plays a role in cell survival and cell adhesion to the endothelium. This protein tends to regulate the activity of CXCR4.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable