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Merck
모든 사진(2)

Key Documents

SAB4502360

Sigma-Aldrich

Anti-PKC δ antibody produced in rabbit

affinity isolated antibody

동의어(들):

KPCD, PKC-δ, PRKCD, kinase PKC-δ, nPKC-δ

로그인조직 및 계약 가격 보기


About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen 77 kDa

종 반응성

human, mouse, rat

농도

~1 mg/mL

기술

ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... PRKCD(5580)

관련 카테고리

일반 설명

Anti-PKC δ antibody detects endogenous levels of total PKC δ protein.
The PKC δ (protein kinase C δ) gene is mapped to human chromosome 3p21.1. It is predominantly expressed in the heart.

면역원

The antiserum was produced against synthesized peptide derived from human PKC delta.

Immunogen Range: 471-520

생화학적/생리학적 작용

The PKC (protein kinase C) protein is known to mediate different cellular processes such as transcription regulation, cell signaling, cell proliferation, immune responses and apoptosis. PKC is also associated with learning ability. Abnormal cell signaling induced by PKC is often observed in cancer. PKC δ (protein kinase C δ) regulates neutrophil migration during sepsis. PKC δ has anticancer effect by reducing the cell proliferation rate and also stimulating apoptosis by arresting cell cycle. PKC δ induces neuron proliferation and survival, thereby it is associated with memory.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

A novel microfluidic assay reveals a key role for protein kinase C ? in regulating human neutrophil-endothelium interaction.
Soroush F
Journal of Leukocyte Biology, 100(5), 1027-1035 (2016)
LAMTOR1-PRKCD and NUMA1-SFMBT1 fusion genes identified by RNA sequencing in aneurysmal benign fibrous histiocytoma with t(3;11)(p21;q13).
Panagopoulos I
Cancer Genetics, 208(11), 545-551 (2015)
MALAT1 in Human Adipose Stem Cells Modulates Survival and Alternative Splicing of PKC?II in HT22 Cells.
El Bassit G
Endocrinology, 158(1), 183-195 (2017)
Polyphenol compounds and PKC signaling.
Das J
Biochimica et Biophysica Acta, 1860(10), 2107-2121 (2016)
Human thrombopoiesis depends on Protein kinase C?/protein kinase C? functional couple.
Carubbi C
Haematologica, 101(7):, 812-820 (2016)

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