추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 86 kDa
종 반응성
rat, human, mouse
농도
~1 mg/mL
기술
ELISA: 1:40000
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... APLP2(334)
일반 설명
Anti-APLP2 Antibody detects endogenous levels of total APLP2 protein.
APLP2 (amyloid precursor-like protein 2) belongs to the amyloid precursor protein family. It is mapped to human chromosome 11q24.
면역원
The antiserum was produced against synthesized peptide derived from human APLP2.
Immunogen Range: 241-290
Immunogen Range: 241-290
생화학적/생리학적 작용
Amyloid precursor-like protein 2 (APLP2) aids in the proliferation of pancreatic cancer growth and metastasis. It controls the expression of cell surface proteins. APLP2 plays an important role in chromosome replication and segregation.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Mechanism for amyloid precursor-like protein 2 enhancement of major histocompatibility complex class I molecule degradation.
The Journal of Biological Chemistry, 284(49), 34296-34307 (2009)
Identification and expression of the first nonmammalian amyloid-beta precursor-like protein APLP2 in the amphibian Xenopus laevis.
European Journal of Biochemistry, 271(10), 1906-1912 (2004)
Oncotarget, 6(4), 2064-2075 (2015-01-13)
Amyloid precursor-like protein 2 (APLP2) is aberrantly expressed in pancreatic cancer. Here we showed that APLP2 is increased in pancreatic cancer metastases, particularly in metastatic lesions found in the diaphragm and intestine. Examination of matched human primary tumor-liver metastasis pairs
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