추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 115 kDa
종 반응성
human, mouse
농도
~1 mg/mL
기술
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TSHZ2(128553)
일반 설명
Anti-TSH2 Antibody detects endogenous levels of total TSH2 protein.
TSH2/TSHZ2 (teashirt zinc finger homeobox 2) is a nuclear protein. It has four zinc-finger (ZF) domains, a homeobox domain and a coiled-coil domain. It is located on human chromosome 20q13.2.
면역원
The antiserum was produced against synthesized peptide derived from human TSH2.
Immunogen Range: 811-860
Immunogen Range: 811-860
생화학적/생리학적 작용
TSH2/TSHZ2 (teashirt zinc finger homeobox 2) acts as a C-terminal binding protein (CtBP)-dependent transcriptional repressor. At the time of mammary tumorigenesis, low level expression of TSH2 liberates GLI1 (glioma-associated oncogene homolog 1) from the nuclear repressor complex to update its transcriptional activity.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Lessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 Mb region of pig chromosome 17
Genome Biology (2007)
Down-regulation of the zinc-finger homeobox protein TSHZ2 releases GLI1 from the nuclear repressor complex to restore its transcriptional activity during mammary tumorigenesis
Oncotarget, 7(5), 5690-5701 (2016)
Nature, 501(7467), 373-379 (2013-09-03)
The complexity of the human brain has made it difficult to study many brain disorders in model organisms, highlighting the need for an in vitro model of human brain development. Here we have developed a human pluripotent stem cell-derived three-dimensional
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