추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 38 kDa
종 반응성
mouse, human, rat
농도
~1 mg/mL
기술
ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... GPR18(2841)
일반 설명
Anti-GPR18 antibody detects endogenous levels of total GPR18 protein. G protein-coupled receptor 18 (GPR18) is made up of 331 amino acids. GPR18 mRNA is located in murine spleen, bone marrow, thymus, lung and cerebellar tissue. This gene is located on human chromosome 13q32.
면역원
The antiserum was produced against synthesized peptide derived from human GPR18.
Immunogen Range: 191-240
Immunogen Range: 191-240
생화학적/생리학적 작용
G protein-coupled receptor 18 (GPR18) participates in cell migration and apoptosis. It modulates mitogen-activated protein kinases (MAPK) activity and immune stimulation.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18
Flegel C, et al.
Scientific Reports, 6, 32255-32255 (2016)
D McHugh
British journal of pharmacology, 167(8), 1575-1582 (2012-05-09)
A review of what is presently known about the G protein coupled receptor GPR18 in terms of its expression and distribution, pharmacology and potential implications for central nervous system and endocannabinoid system signalling. LINKED ARTICLES This article is part of
Linda Console-Bram et al.
British journal of pharmacology, 171(16), 3908-3917 (2014-04-26)
GPR18 is a candidate cannabinoid receptor, but its classification as such is controversial. The rationale of the study presented herein was to consider the effects of N-arachidonoyl glycine (NAGly) and cannabinoids via differential G-protein coupled pathways, in addition to β-arrestin
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