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Merck
모든 사진(3)

Key Documents

SAB4500900

Sigma-Aldrich

Anti-LMTK2 antibody produced in rabbit

affinity isolated antibody

동의어(들):

Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2, Serine/threonine protein kinase KPI-2

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen 164 kDa

종 반응성

human

농도

~1 mg/mL

기술

ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... LMTK2(22853)

일반 설명

Anti-LMTK2 antibody detects endogenous levels of total LMTK2 protein.
Lemur tyrosine kinase 2 (LMTK2) is a serine/threonine kinase, located in endosomal compartments. It is also termed as BREK (brain-enriched kinase), AATYK-2 (apoptosis-associated tyrosine kinase 2), cdk5, KPI-2 and Cprk. It is expressed at high levels in the plasma membrane. LMTK2 consists of 1503 amino acids and is located on human chromosome 7q21.

면역원

The antiserum was produced against synthesized peptide derived from human LMTK2.

Immunogen Range: 651-700

애플리케이션

Anti-LMTK2 antibody has been used in western blotting.

생화학적/생리학적 작용

Lemur tyrosine kinase 2 (LMTK2) participates in endosomal membrane trafficking and neuronal physiology. It also participates in the differentiation of tissues and acts as a negative regulator of nerve growth factor (NGF)-induced neuronal differentiation.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers?
Wiklund F
Genome Medicine, 2(7), 45-45 (2010)
Determination of the membrane topology of lemur tyrosine kinase 2 (LMTK2) by fluorescence protease protection
Nixon A, et al.
American Journal of Physiology. Cell Physiology, 304(2), C164-C164 (2013)
Daniel F Cruz et al.
Frontiers in oncology, 11, 596861-596861 (2021-04-06)
Lemur tyrosine kinase 2 (LMTK2) is a transmembrane Ser/Thr kinase whose role has been increasingly recognized; however, when compared to other kinases, understanding of the LMTK2 networks and biological functions is still limited. Recent data have shown that transforming growth
Signal dependent ER export of lemur tyrosine kinase 2
Butler EC and Bradbury NA
BMC Cell Biology, 16(1), 26-26 (2015)
Lemur tyrosine kinase 2 (LMTK2) is a determinant of cell sensitivity to apoptosis by regulating the levels of the BCL2 family members
Conti A, et al.
Cancer Letters, 389, 59-69 (2017)

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