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Merck
모든 사진(1)

주요 문서

SAB4200718

Sigma-Aldrich

Anti-Elastin antibody, Mouse monoclonal

clone BA-4, purified from hybridoma cell culture

동의어(들):

Anti-ELN, Anti-Tropoelastin

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified from hybridoma cell culture

항체 생산 유형

primary antibodies

클론

BA-4, monoclonal

양식

buffered aqueous solution

종 반응성

sheep, hamster, bovine, goat, frog, rabbit, porcine, human, guinea pig, canine

농도

~1.0 mg/mL

기술

immunoblotting: suitable
immunohistochemistry: 10-20 μg/mL using enzyme-retrieved formalin-fixed, paraffin-embedded sheep arterial tissue sections
immunoprecipitation (IP): suitable

동형

IgG1

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... EMILIN3(2006)

일반 설명

Anti-Elastin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the BA-4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with bovine alpha-Elastin.

면역원

bovine alpha-Elastin

애플리케이션

Anti-Elastin antibody, Mouse monoclonal has been used in:
  • immunohistochemistry
  • immunoblot
  • immunoprecipitation

생화학적/생리학적 작용

Elastin (ELN) provides elasticity and is integrated with other proteins from the ECM in elastic fibrils. Elastin undergoes changes of morphology with aging and at many disease states. In addition, several heritable diseases, such as supravalvular aortic stenosis, cutis laxa, Marfan syndrome, pseudoxanthoma elasticum and Buschke-Ollendorf syndrome, may result from molecular defects of elastin.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Elastin
Biochemistry of Collagens, Laminins and Elastin, 197-201 (2016)
Elastic fibres in health and disease
Baldwin AK, et al.
Expert Reviews in Molecular Medicine, 15 (2013)
Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly
Hinek A and Wilson SE
The American Journal of Pathology, 156(3), 925-938 (2000)
Elastogenesis in human arterial disease: a role for macrophages in disordered elastin synthesis.
Krettek A, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 23(4), 582-587 (2003)

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