추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
형태
buffered aqueous solution
종 반응성
human, mouse
농도
~1.0 mg/mL
기술
immunoblotting: 2.5-5.0 μg/mL using whole extracts of mouse P19 cells.
immunofluorescence: 2.5-5.0 μg/mL using human HeLa cells.
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CHD1(1105)
mouse ... Chd1(12648)
일반 설명
Chromodomain-helicase-DNA-binding protein 1 (CHD1) is an ATP-dependent chromatin-remodeling factor. The CHD family of proteins contains two domains : chromo (chromatin organization modifier) and SNF2-related helicase/adenosine triphosphatase (ATPase).
면역원
synthetic peptide corresponding to the C-terminal region of human CHD1 , conjugated to KLH.
애플리케이션
Anti-CHD1 (C-terminal) antibody from rabbit has been used in immunoblotting and immunofluorescence.
생화학적/생리학적 작용
Chromodomain-helicase-DNA-binding protein 1 (CHD1) modifies chromatin structure affecting the interaction of transcriptional apparatus to its chromosomal DNA template. CHD1 is required for maintaining open chromatin and pluripotency in embryonic stem cells (ESCs).
물리적 형태
a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Glenn Hauk et al.
Current opinion in structural biology, 21(6), 719-727 (2011-10-15)
This review focuses on recent structural insights into regulation and nucleic acid binding of Superfamily 2 (SF2)-type helicases as they relate to chromatin remodelers. We review structural features of the Chd1 chromatin remodeler regarding regulation of the ATPase motor, and
Lena Ho et al.
Nature, 463(7280), 474-484 (2010-01-30)
New methods for the genome-wide analysis of chromatin are providing insight into its roles in development and their underlying mechanisms. Current studies indicate that chromatin is dynamic, with its structure and its histone modifications undergoing global changes during transitions in
Concetta G A Marfella et al.
Mutation research, 618(1-2), 30-40 (2007-03-14)
Chromatin remodeling enzymes contribute to the dynamic changes that occur in chromatin structure during cellular processes such as transcription, recombination, repair, and replication. Members of the chromodomain helicase DNA-binding (Chd) family of enzymes belong to the SNF2 superfamily of ATP-dependent
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.