콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

SAB4200197

Sigma-Aldrich

Anti-Periostin antibody,Mouse monoclonal

clone 47, purified from hybridoma cell culture

동의어(들):

Periostin Antibody, Periostin Antibody - Monoclonal Anti-Periostin antibody produced in mouse, Anti-OSF2, Anti-Osteoblast specific factor 2, Anti-PDLPOSTN, Anti-POSTN

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

결합

unconjugated

항체 형태

purified from hybridoma cell culture

항체 생산 유형

primary antibodies

클론

47, monoclonal

형태

buffered aqueous solution

분자량

antigen ~88 kDa

종 반응성

human

농도

~1.0 mg/mL

기술

western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin

동형

IgG1

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... POSTN(10631)

일반 설명

Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.

면역원

human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.

애플리케이션

Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.

생화학적/생리학적 작용

Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

적합한 제품을 찾을 수 없으신가요?  

당사의 제품 선택기 도구.을(를) 시도해 보세요.

Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Imaging of secreted extracellular periostin, an important marker of invasion in the tumor microenvironment in esophageal cancer.
Heidari P, et al.
Journal of Nuclear Medicine, 56(8), 1246-1246 (2015)
Epithelial periostin expression is correlated with poor survival in patients with invasive breast carcinoma.
Kim G E, et al.
PLoS ONE, 12(11), e0187635-e0187635 (2017)
Functional role of periostin in development and wound repair: implications for connective tissue disease.
Hamilton D W.
Journal of Cell Communication and Signaling, 2(1-2), 9-9 (2008)
Bone marrow mesenchymal stem cells promote head and neck cancer progression through Periostin?mediated phosphoinositide 3?kinase/Akt/mammalian target of rapamycin.
Liu C, et al.
Cancer Science, 109(3), 688-698 (2018)
Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.
Makita K, et al.
International Archives of Allergy and Immunology, 175(1-2), 26-35 (2018)

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.