추천 제품
일반 설명
Hemagglutinin [Influenza A virus (A/chicken/Jilin/9/ 2004(H5N1))] is the principal surface antigen of influenza A virus. Hemagglutinin (HA) is a homotrimer; each monomer is a single polypeptide (HA0) that is post transcriptionally cleaved by host proteases into two subunits (HA1 and HA2). HA2 is highly conserved across different strains of influenza virus. HA preferentially binds to α2-3 sialic acid receptor in aves, whereas in human it binds to α2-6 sialic acid receptor.
면역원
Antibody was raised against a peptide corresponding to 13 amino acids in the middle of the Hemagglutinin protein.
생화학적/생리학적 작용
Hemagglutinin (HA), specially HA2 is responsible for the binding of the virus to host receptors and enables its entry into the host cell through endocytosis through endosomal membrane fusion. HA is the primary target for neutralizing antibodies. HA is a potent target for drug and vaccine development.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Monoclonal antibodies against the fusion peptide of hemagglutinin protect mice from lethal influenza A virus H5N1 infection
Journal of Virology, 83(6), 2553-2562 (2009)
Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus.
Science, 312(5772), 404-410 (2006)
The Journal of infectious diseases, 181(1), 344-348 (1999-12-23)
The first outbreak of avian influenza A (H5N1) occurred among humans in Hong Kong in 1997. To estimate the risk of person-to-person transmission, a retrospective cohort study was conducted to compare the prevalence of H5N1 antibody among health care workers
Virology, 252(2), 331-342 (1999-01-08)
The transmission of avian H5N1 influenza viruses to 18 humans in Hong Kong in 1997 with six deaths established that avian influenza viruses can transmit to and cause lethal infection in humans. This report characterizes the antigenic and biological properties
Veterinary microbiology, 74(1-2), 3-13 (2000-05-09)
Only type A influenza viruses are known to cause natural infections in birds, but viruses of all 15 haemagglutinin and all nine neuraminidase influenza A subtypes in the majority of possible combinations have been isolated from avian species. Influenza A
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