SAB4200190

Anti-Sumo-2/3 antibody, Rat monoclonal

clone 3H12, purified from hybridoma cell culture

• 동의어(들): Anti-HSMT3, Anti-MGC117191, Anti-SMT3 homolog 2, Anti-SMT3 suppressor of mif two 3 homolog 2, Anti-SMT3B, Anti-SMT3H2, Anti-sentrin 2, Anti-small ubiquitin-like modifier 2, Anti-small ubiquitin-related modifier 2, Anti-ubiquitin-like protein SMT3B, Monoclonal Anti-Sumo-2/3, SUMO-2/3, SUMO2/3
• MDL number: MFCD03455941
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 결합: unconjugated
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: 3H12, monoclonal
• 형태: buffered aqueous solution
• 분자량: ~11 kDa
• 종 반응성: mouse, rat, human
• 농도: ~1.0 mg/mL
• 기술: immunocytochemistry: suitable; western blot: 2-4 μg/mL using HeLa cell nuclear extract
• UniProt 수납 번호: P55854
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SUMO3(6612) ; mouse ... Sumo3(20610) ; rat ... Sumo3(499417)

설명

일반 설명

Monoclonal Anti-Sumo-2/3 (rat IgG2a isotype) is derived from the hybridoma 3H12 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a human SUMO3 fusion protein.

Small ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm.

면역원

human SUMO3 fusion protein

애플리케이션

Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and immunocytochemistry.

생화학적/생리학적 작용

Small ubiquitin-like modifier (SUMO) was identified as a post-translational protein modifier.

Small ubiquitin-like modifier 3 (SUMO3) plays a vital role in enhancing cellular responses to environmental stress. It acts as a key element of the leukemogenic network in transient myeloproliferative disorder (TMD) of the newborn/acute megakaryoblastic leukaemia (AMKL).

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable