SAB3500711

Anti-TET2 antibody produced in rabbit

affinity isolated antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 분자량: 220 kDa
• 종 반응성: human
• 농도: 1 mg/mL
• 기술: ELISA: suitable; western blot: suitable
• NCBI 수납 번호: NP_001120680
• UniProt 수납 번호: Q6N021
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TET2(54790)

설명

일반 설명

Tet methylcytosine dioxygenase 2 (TET2) is part of the Fe(II)/α-ketoglutarate-dependent dioxygenase family of enzymes. It is expressed in the brain. The gene encoding TET2 is localized on human chromosome 4q24.

면역원

Antibody was raised against an 18 amino acid peptide near the amino terminus of human TET2.

애플리케이션

Anti-TET2 antibody produced in rabbit has been used in Western blotting.

생화학적/생리학적 작용

Tet methylcytosine dioxygenase 2 (TET2) is involved in the conversion of 5-methylcytosine to 5-hydroxymethyl-cytosine (5hmC). It also has a role in stimulating DNA demethylation and lymphomagenesis. Mutations in the gene encoding TET2 have been linked to myelodysplastic syndromes.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500711.

물리적 형태

Supplied at 1 mg/mL in PBS with 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable