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Merck
모든 사진(1)

Key Documents

SAB3500380

Sigma-Aldrich

Anti-LXR-B antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-LXRB, Anti-Liver X receptor B, Anti-NR1H2, Anti-Nuclear receptor subfamily 1 group H member 2

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

mouse, human, rat

기술

indirect ELISA: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... NR1H2(7376)

일반 설명

Liver X receptor β (LXRβ ) is a member of LXRs that belong to the nuclear receptor superfamily. It possesses a DNA-binding domain that requires the ligand-binding domain to heterodimerize with a retinoid X receptor partner for its DNA-binding activity. The protein is expressed in many tissues and the LXRβ gene is localized on human chromosome 19q13.3.

면역원

LXR-B antibody was raised against a 14 amino acid peptide from near the amino terminus human LXR-B.

생화학적/생리학적 작용

Liver X receptor β (LXRβ) has a role in cell death and cholesterol metabolism. LXRs have been found to regulate inflammatory response in macrophages. They are also involved in the regulation of cell proliferation.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

결합

The action of this antibody can be blocked using blocking peptide SBP3500380.

물리적 형태

Supplied in PBS with 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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관련 제품

제품 번호
설명
가격

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.
Mouzat K
BMC Medical Genetics (2011)
Liver X receptor ? activation induces pyroptosis of human and murine colon cancer cells.
Derangere V
Cell Death and Differentiation (2014)
Liver x receptors in atherosclerosis and inflammation.
Im SS and Osborne TF
Circulation Research (2011)

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