SAB2701977

Anti-DBH antibody produced in rabbit

• 동의어(들): DBM
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: liquid
• 분자량: 69 kDa
• 종 반응성: mouse, human, rat
• 농도: 1 mg/mL
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:1,000; western blot: 1:500-1:3,000
• UniProt 수납 번호: P09172
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... DBH(1621)

설명

일반 설명

Dopamine-β-hydroxylase (DBH) is found in the nuclei of noradrenergic and dopaminergic neurons. The DBH gene is mapped on the human chromosome at 9q34.2.

면역원

Recombinant fragment corresponding to a region within amino acids 8 and 320 of Dopamine beta Hydroxylase (Uniprot ID#P09172)

애플리케이션

Anti-DBH antibody produced in rabbit has been used in immunohistochemistry (1:200) (1:1000).

생화학적/생리학적 작용

Dopamine-β-hydroxylase (DBH) protein plays a role in the conversion of dopamine to noradrenaline. This protein is implicated in various disorders such as Huntington′s chorea, hypertension, Parkinson′s, and smoking disorders. DBH protein is also implicated in heart failure and mental disorders like depression, Tourette syndrome, and schizophrenia. Lower levels of DHB plasma are seen in patients with bipolar disorders and unipolar psychotic depression. Higher levels of DBH plasma are observed in patients with severe depression.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317,H412
• 예방조치 성명서: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 3 - Skin Sens. 1
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable