추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
saturated ammonium sulfate (SAS) precipitated
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
종 반응성
human
기술
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... KLF4(9314)
일반 설명
Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.
면역원
KLF4 (NP_004226.3, )
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.
생화학적/생리학적 작용
Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.
물리적 형태
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Dynamic down-regulation of Kruppel-like factor 4 in colorectal adenoma-carcinoma sequence.
Journal of Cancer Research and Clinical Oncology (2008)
Kruppel-like factor 4 (KLF4): What we currently know.
Gene (2017)
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
The Journal of Biological Chemistry (2007)
KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma
The American Journal of Pathology (2011)
Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells
Stem Cell Reviews (2010)
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