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Merck
모든 사진(1)

Key Documents

SAB1300678

Sigma-Aldrich

Anti-KLF4 antibody produced in rabbit

saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

동의어(들):

Anti-EZF, Anti-GKLF, Anti-Kruppel-like factor 4

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

saturated ammonium sulfate (SAS) precipitated

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

human

기술

indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... KLF4(9314)

일반 설명

Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2.

면역원

KLF4 (NP_004226.3, )
This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4.

생화학적/생리학적 작용

Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells.

물리적 형태

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Dynamic down-regulation of Kruppel-like factor 4 in colorectal adenoma-carcinoma sequence.
Xu J
Journal of Cancer Research and Clinical Oncology (2008)
Kruppel-like factor 4 (KLF4): What we currently know.
Ghaleb AM and Yang VW
Gene (2017)
Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
Evans PM
The Journal of Biological Chemistry (2007)
KLF4 is a Novel Candidate Tumor Suppressor Gene in Pancreatic Ductal Carcinoma
Francesca Zammarchi
The American Journal of Pathology (2011)
Advances in Reprogramming Somatic Cells to Induced Pluripotent Stem Cells
Minal Patel
Stem Cell Reviews (2010)

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