S8884

Safranin O

Dye content, ≥80%, certified by the Biological Stain Commission, powder

• 동의어(들): Basic Red 2, Cotton Red, Gossypimine, Safranin T, Safranin Y or A
• 실험식(Hill 표기법): C₂₀H₁₉ClN₄
• CAS Number: 477-73-6
• Molecular Weight: 350.84
• 색상 지수 번호: 50240
• Beilstein: 3924099
• EC Number: 207-518-8
• MDL number: MFCD00011759
• UNSPSC 코드: 12171500
• PubChem Substance ID: 24899820
• NACRES: NA.47

속성

• product name: Safranin O, certified by the Biological Stain Commission
• Grade: certified by the Biological Stain Commission
• 형태: powder
• 구성: Dye content, ≥80%
• 색상: green to very dark green
• solubility: H₂O: 1 mg/mL
• 응용 분야: diagnostic assay manufacturing; hematology; histology
• 저장 온도: room temp
• SMILES string: [Cl-].Cc1cc2nc3cc(C)c(N)cc3[n+](-c4ccccc4)c2cc1N
• InChI: 1S/C20H18N4.ClH/c1-12-8-17-19(10-15(12)21)24(14-6-4-3-5-7-14)20-11-16(22)13(2)9-18(20)23-17;/h3-11H,1-2H3,(H3,21,22);1H
• InChI key: OARRHUQTFTUEOS-UHFFFAOYSA-N

설명

일반 설명

Safranin O is a metachromatic, cationic dye. It is used as a counterstain in Gram staining. The stain colors Gram-negative bacteria pink to red and has no effect on Gram-positive bacteria. It is also used to assess glycosaminoglycans (GAGs) in cartilage. The dye imparts an intense red to GAGs. It easily binds to polyanions.

애플리케이션

Safranin O has been used in the staining of extraocular muscle mesenchymal stem cells (EOM-MSC) for the detection of cartilage, mucin and mast cell granules It has also been used as a mediator dye in cytochrome P450 spectral assay.

Safranin O has been used to stain matrix proteoglycans to study cartilaginous tissue structural integrity in mice. It has also been used to stain chondrogenically differentiated human bone marrow stromal cells.

적합성

Certified as a stain for chromosomes in the Flemming triple stain; to stain gram negative bacteria in the Gram stain procedure; Safranine-fast green FCF stain for plant cells.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H318
• 예방조치 성명서: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves