S1875

(−)-Scopolamine hydrobromide trihydrate

≥98% (HPLC), powder

• 동의어(들): Hyoscine hydrobromide, Scopine tropate
• 실험식(Hill 표기법): C₁₇H₂₁NO₄ · HBr · 3H₂O
• CAS Number: 6533-68-2
• Molecular Weight: 438.31
• Beilstein: 6100669
• MDL number: MFCD00150066
• UNSPSC 코드: 12352116
• PubChem Substance ID: 24277871
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 형태: powder
• 광학 활성: [α]25/D −24 to −26°, c = 5 in H₂O(lit.)
• 색상: white to off-white
• mp: 195-199 °C (dry matter) (lit.)
• solubility: H₂O: 50 mg/mL
• SMILES string: O.O.O.Br.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.BrH.3H2O/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;;;;/h2-6,11-16,19H,7-9H2,1H3;1H;3*1H2/t11-,12-,13-,14+,15-,16+;;;;/m1..../s1
• InChI key: LACQPOBCQQPVIT-SEYKEWMNSA-N
• 유전자 정보: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

설명

생화학적/생리학적 작용

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330
• 예방조치 성명서: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges