S0577

Streptokinase C from Streptococcus sp.

lyophilized solid, ≥3,500 unit/mg solid

• 동의어(들): Streptokinase
• 효소 위원회 번호: 3.4.99.0 (BRENDA, IUBMB)
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 생물학적 소스: bacterial (Streptococcus sp.)
• Quality Level: 200
• 재조합: expressed in E. coli
• 분석: 40—60% protein (biuret)
• 양식: lyophilized solid
• 특이 활성도: ≥3,500 unit/mg solid
• 색상: off-white to light yellow
• 응용 분야: life science and biopharma
• 저장 온도: −20°C
• 유전자 정보: Streptococcus pyogenes ... SKC(134997)

설명

일반 설명

Research area: Cell Signaling

Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β-hemolytic Streptococci. It is composed of multiple structural domains like α-, β-, and γ-domains that are involved in various functions.

애플리케이션

Streptokinase C from Streptococcus sp. has been used to quantitate the survival of Staphylococcus aureus in whole human blood.

생화학적/생리학적 작용

Streptokinase shows fibrinolytic activity by triggering the circulatory plasminogen either via a fibrin-dependent or fibrin-independent mechanism. Streptokinase has been studied majorly in terms of its therapeutic efficacy and treating myocardial infarction to dissolve clots.

단위 정의

One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min.

물리적 형태

Lyophilized powder containing approx. 50% bovine serum albumin (total protein by biuret) with sodium glutamate.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable