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Merck
모든 사진(1)

주요 문서

RAB1476

Sigma-Aldrich

Human GAPHD ELISA

for serum, plasma and cell culture supernatants

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About This Item

UNSPSC 코드:
41116158
NACRES:
NA.32

종 반응성

human

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable

입력

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.82 ng/mL
standard curve range: 0.819-200 ng/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... GAPDH(2597)

일반 설명

The GAPHD (glyceraldehyde-3-phosphate dehydrogenase) gene is mapped to human chromosome 12p13.31. GAPHD encodes a multifunctional protein which is a glycolytic enzyme.
This ELISA antibody pair detects human GAPHD. Other species not yet determined.

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

생화학적/생리학적 작용

GAPHD (glyceraldehyde-3-phosphate dehydrogenase) is associated with the progression of Huntington′s disease by increasing cytotoxicity. Gaphd is often referred to as glycolytic enzyme and catalyzes the sixth step in glycolysis. The Gaphd enzyme possess uracil-DNA glycosylase activity. The enzyme regulates transcription, posttranscriptional gene expression, intracellular membrane trafficking and apoptosis.

기타 정보

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

픽토그램

Corrosion

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) aggregation causes mitochondrial dysfunction during oxidative stress-induced cell death.
Nakajima H, et al.
The Journal of Biological Chemistry (2017)
A hydrocortisone derivative binds to GAPDH and reduces the toxicity of extracellular polyglutamine-containing aggregates.
Lazarev V F, et al.
Biochemical and Biophysical Research Communications, 487(3), 723-727 (2017)
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in DNA repair
Kosova A A, et al.
Biochemistry (Moscow), 82(6), 643-654 (2017)
Prediction of potential cancer-risk regions based on transcriptome data: towards a comprehensive view.
Alisoltani A, et al.
PLoS ONE, 9(5), e96320-e96320 (2014)

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