RAB1378

Human CMG-2 ELISA

for serum, plasma and cell culture supernatants

• UNSPSC 코드: 41116158
• NACRES: NA.32

속성

• 종 반응성: human
• 기술: ELISA: suitable
• 입력: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... ANTXR2(118429)

설명

일반 설명

Anthrax toxin receptor (ANTXR2), also known as capillary morphogenesis protein gene-2 (CMG2), is encoded by the gene mapped to human chromosome 24q21. CMG2 is a ubiquitously expressed type I transmembrane protein. It contains von Willebrand A (vWA) domain that is involved in binding lamin and collagen IV.

This ELISA antibody pair detects Human CMG-2. Other species not yet determined.

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

생화학적/생리학적 작용

Anthrax toxin receptor (ANTXR2)/ capillary morphogenesis protein gene-2 (CMG2) has been implicated in basement-membrane matrix assembly and endothelial cell morphogenesis. CMG2 acts as a chief receptor for anthrax in vivo. It stimulates the anthrax toxin activity by equipping toxin with a high-affinity binding anchor on the cell membrane and a path of entry into the host cell. Mutation in the gene is associated with the development of rare, autosomal recessive disorders called, Juvenile hyaline fibromatosis (JHF) and infantile systemic hyalinosis (ISH).

기타 정보

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

안전성 정보

• 픽토그램: GHS05
• 신호어: Warning
• 유해 및 위험 성명서: H290
• 예방조치 성명서: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable