추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type: human cell lysate
assay range
inter-assay cv: <10%
intra-assay cv: <12%
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... FER(2241)
일반 설명
FER (fps/fes related) tyrosine kinase is encoded by the gene mapped to human chromosome 5q21.3. Tyrosine kinase is a cytoplasmic protein characterized with a single SH2 domain and an extensive amino terminus. The encoded protein is ubiquitously expressed.
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-FER.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
생화학적/생리학적 작용
FER tyrosine kinase induces signal transduction at the plasma membrane. It is implicated in the regulation of cell-cell adhesion. FER tyrosine kinase interacts with phosphatidic acid (PA) to enhance phosphorylation of cortactin, a protein that promotes actin.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Characterization of a de novo balanced translocation in a patient with moderate mental retardation and dysmorphic features
Haddad M R, et al.
European Journal of Medical Genetics, 52(4), 211-217 (2009)
A curvature-dependent membrane binding by tyrosine kinase Fer involves an intrinsically disordered region.
Yamamoto H, et al.
Biochemical and Biophysical Research Communications, 495(1), 1522-1527 (2018)
The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.
Kim L and Wong T W
Molecular Cell Biology, 15(8), 4553-4561 (1995)
The Tyrosine Kinase Fer Is a Downstream Target of the PLD-PA Pathway that Regulates Cell Migration
Itoh T, et al.
Science Signaling, 2(87), ra52-ra52 (2009)
Naoko Kogata et al.
Molecular biology of the cell, 14(9), 3553-3564 (2003-09-16)
Platelet endothelial adhesion molecule-1 (PECAM-1) is a part of intercellular junctions and triggers intracellular signaling cascades upon homophilic binding. The intracellular domain of PECAM-1 is tyrosine phosphorylated upon homophilic engagement. However, it remains unclear which tyrosine kinase phosphorylates PECAM-1. We
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.