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Merck
모든 사진(1)

주요 문서

RAB0751

Sigma-Aldrich

Human UMOD / Uromodulin ELISA Kit

동의어(들):

THP, Tamm-Horsfall protein, Tamm-Horsfall urinary glycoprotein, Uromodulin

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About This Item

UNSPSC 코드:
41116158
NACRES:
NA.84

종 반응성

human

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable

입력

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 40 pg/mL
standard curve range: 40.96-10000 pg/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... UMOD(7369)

일반 설명

The UMOD ELISA kit provides for the Quantitative measurement of Uromodulin in Cell Culture Supernatants, Plasma and Serum.
Uromodulin also known as Tamm-Horsfall protein (THP) is a glycoprotein localized in the thick ascending limb (TAL) of the Henle loop in the kidney. It is the most abundant protein excreted in the urine. Uromodulin plays a role in preventing urinary tract infections and kidney stones. It aids in immunomodulation and regulation of ion transport in TAL. Uromodulin acts as an inverse biomarker in the early detection of chronic kidney disorders.

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human UMOD / Uromodulin ELISA Kit has been used to measure the levels of Tamm-Horsfall protein (THP) in human plasma samples.

기타 정보

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

키트 구성품 역시 별도로 이용 가능함

제품 번호
설명
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

픽토그램

Corrosion

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Olivier Devuyst et al.
Nature reviews. Nephrology, 13(9), 525-544 (2017-08-07)
Uromodulin (also known as Tamm-Horsfall protein) is exclusively produced in the kidney and is the most abundant protein in normal urine. The function of uromodulin remains elusive, but the available data suggest that this protein might regulate salt transport, protect
Kaice A LaFavers et al.
Science translational medicine, 11(512) (2019-10-04)
High serum concentrations of kidney-derived protein uromodulin [Tamm-Horsfall protein (THP)] have recently been shown to be independently associated with low mortality in both older adults and cardiac patients, but the underlying mechanism remains unclear. Here, we show that THP inhibits

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