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Merck
모든 사진(1)

주요 문서

R1908

Sigma-Aldrich

Remifentanil hydrochloride

≥97% (HPLC), powder

동의어(들):

3-[methoxycarbonyl-4-[(1-oxopropyl)phenylamino]1-piperidine]propanoic acid methyl ester hydrochloride, GI-87084B, Remifentanyl, Ultiva

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About This Item

실험식(Hill 표기법):
C20H28N2O5·HCl
CAS Number:
Molecular Weight:
412.91
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:

Quality Level

분석

≥97% (HPLC)

양식

powder

약물 제어

USDEA Schedule II; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

저장 조건

desiccated

색상

white to off-white

solubility

H2O: ≥20 mg/mL

저장 온도

2-8°C

SMILES string

O=C(CC)N(C1(CCN(CCC(OC)=O)CC1)C(OC)=O)C2=CC=CC=C2.[H]Cl

InChI

1S/C20H28N2O5.ClH/c1-4-17(23)22(16-8-6-5-7-9-16)20(19(25)27-3)11-14-21(15-12-20)13-10-18(24)26-2;/h5-9H,4,10-15H2,1-3H3;1H

InChI key

WFBMIPUMYUHANP-UHFFFAOYSA-N

유전자 정보

human ... OPRM1(4988)

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관련 카테고리

생화학적/생리학적 작용

Remifentanil hydrochloride is a mu opioid receptor agonist, anesthetic, and analgesic compound.
Remifentanil hydrochloride is a mu opioid receptor agonist, anesthetic, and analgesic compound. Remifentanil was developed as an ultra-short-acting mu opioid receptor agonist with improved pharmacodynamic properties.

특징 및 장점

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

픽토그램

Health hazard

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

STOT SE 2

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Anthony G Doufas et al.
PloS one, 8(1), e54807-e54807 (2013-02-06)
Obstructive sleep apnea (OSA) is characterized by recurrent nocturnal hypoxia and sleep disruption. Sleep fragmentation caused hyperalgesia in volunteers, while nocturnal hypoxemia enhanced morphine analgesic potency in children with OSA. This evidence directly relates to surgical OSA patients who are
Clément Marcelin et al.
Journal of vascular and interventional radiology : JVIR, 29(7), 975-980 (2018-05-08)
To evaluate the safety and efficacy of endovascular management of pulmonary artery lesions caused by lung tumors. Nineteen patients (15 men, 4 women; average age: 60.3 years, range, 51-86 years) treated for massive or recurrent hemoptysis with transarterial pulmonary artery
N A Pedersen et al.
Acta anaesthesiologica Scandinavica, 57(8), 988-995 (2013-07-10)
Magnetic resonance imaging (MRI) of children is generally performed under sedation or with general anaesthesia (GA), but the ideal regimen has not been found. The aim of this study was to see if propofol-remifentanil would be a suitable alternative for
Arne Kristian Skulberg et al.
European journal of clinical pharmacology, 74(7), 873-883 (2018-03-24)
This study aimed to develop a model for pharmacodynamic and pharmacokinetic studies of naloxone antagonism under steady-state opioid agonism and to compare a high-concentration/low-volume intranasal naloxone formulation 8 mg/ml to intramuscular 0.8 mg. Two-way crossover in 12 healthy volunteers receiving naloxone while
T M Hemmerling et al.
British journal of anaesthesia, 110(6), 1031-1039 (2013-02-22)
We have developed an automatic anaesthesia system for closed-loop administration of anaesthesia drugs. The control variables used were bispectral index (BIS) and Analgoscore for hypnosis and antinociception, respectively. One hundred and eighty-six patients were randomly enrolled in two groups. Propofol

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