Q0632

Quinapril hydrochloride

≥98% (HPLC), solid

• 동의어(들): (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
• 실험식(Hill 표기법): C₂₅H₃₀N₂O₅ · HCl
• CAS Number: 82586-55-8
• Molecular Weight: 474.98
• MDL number: MFCD00889215
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329823858
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: white
• solubility: H₂O: >10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(O)=O
• InChI: 1S/C25H30N2O5.ClH/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30;/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30);1H/t17-,21-,22-;/m0./s1
• InChI key: IBBLRJGOOANPTQ-JKVLGAQCSA-N
• 유전자 정보: human ... ACE(1636)

설명

애플리케이션

Quinapril hydrochloride has been used as an angiotensin-converting enzyme (ACE) inhibitor to study its effects on renal tubular epithelial cell proliferation in human renal tubular epithelial cells. It has also been used as an ACE inhibitor to evaluate its effects on the expression of angiotensin II (AII) in patient-derived Atheroma samples.

생화학적/생리학적 작용

Quinapril has been studied to exhibit therapeutic effects against hypertension and congestive heart failure.

Quinapril is a short-acting angiotensin converting enzyme (ACE) inhibitor.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H361d,H372
• 예방조치 성명서: P202 - P260 - P264 - P280 - P308 + P313 - P405
• Hazard Classifications: Repr. 2 - STOT RE 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)