PZ0359

PF-06827443

≥98% (HPLC)

• 동의어(들): 2-((3R,4S)-3-Hydroxytetrahydro-pyran-4-yl)-5-methyl-6-(4-oxazol-4-yl-benzyl)-2,3-dihydro-isoindol-1-one
• 실험식(Hill 표기법): C₂₄H₂₄N₂O₄
• CAS Number: 2115022-67-6
• Molecular Weight: 404.46
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: room temp
• SMILES string: CC1=CC(CN([C@@H]2[C@@H](O)COCC2)C3=O)=C3C=C1CC4=CC=C(C5=COC=N5)C=C4
• InChI: 1S/C24H24N2O4/c1-15-8-19-11-26(22-6-7-29-13-23(22)27)24(28)20(19)10-18(15)9-16-2-4-17(5-3-16)21-12-30-14-25-21/h2-5,8,10,12,14,22-23,27H,6-7,9,11,13H2,1H3/t22-,23-/m0/s1
• InChI key: RBMHKFVYRIRMOG-GOTSBHOMSA-N

설명

생화학적/생리학적 작용

PF-06827443 is a otent, low clearance, orally bioavailable, and CNS penetrant muscarinic M1-selectivepositive allosteric modulator (PAM) with minimal agonist activity.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable