PZ0284

PF-04753299

≥98%

• 동의어(들): α(R)-N-Hydroxy-α-methyl-α-(methylsulfonyl)-[1,1′-biphenyl]-4-butanamide, (+)-(2R)-4-(Biphenyl-4-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, (2R)-4-Biphenyl-4-yl-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide, PF 04753299, PF-4753299
• 실험식(Hill 표기법): C₁₈H₂₁NO₄S
• CAS Number: 1289620-49-0
• Molecular Weight: 347.43
• MDL number: MFCD22683864
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329823811
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98%
• 양식: powder
• 색상: white to light brown
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: O=C(NO)[C@@](S(=O)(C)=O)(C)CCC(C=C1)=CC=C1C2=CC=CC=C2
• InChI: 1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1
• InChI key: GDYIQUFNICPYHF-GOSISDBHSA-N

설명

생화학적/생리학적 작용

PF-04753299 is a potent and selective inhibitor of LpxC (UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase) that is effective in a murine of gram-negative bacteria infection model.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable