PZ0035

Sutezolid

≥98% (HPLC)

• 동의어(들): (S)-N-[[3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide, PNU-100480, PNU100480
• 실험식(Hill 표기법): C₁₆H₂₀FN₃O₃S
• CAS Number: 168828-58-8
• Molecular Weight: 353.41
• MDL number: MFCD00937821
• UNSPSC 코드: 51111800
• PubChem Substance ID: 329823692
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 광학 활성: [α]/D -8 to -12°, c = 1 in chloroform-d
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: room temp
• SMILES string: FC1=CC(N(C[C@H](CNC(C)=O)O2)C2=O)=CC=C1N3CCSCC3
• InChI: 1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
• InChI key: FNDDDNOJWPQCBZ-ZDUSSCGKSA-N

설명

생화학적/생리학적 작용

Sutezolid (PNU 100480) is an oxazolidinone antimicrobial. Sutezolid inhibits protein synthesis by inhibiting bacterial mRNA translation. Sutezolid is being investigated for the treatment of multiple drug–resistant and extensively drug-resistant tuberculosis. The compound is a less toxic and more potent derivative of linezolid.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable